Routine Pregnancy Tests

lab test pregnancy Several laboratory tests will be done during your prenatal visits. The results of tests will be noted in your medical record. Other tests may be suggested depending on your medical history, family background, race, or the results of your first exam.

Screening tests are available that give information about a pregnant woman’s risk of having a baby with a certain birth defects such as Down Syndrome and spina bifida.

This table lists the tests you can expect during pregnancy. If a test indicates a possible problem, further testing and appropriate treatment will be started.

 

Test Purpose Comments
A pelvic (vaginal) examination First or second prenatal visit:

  • To confirm pregnancy
  • To correlate size of uterus with date of last menstrual period
  • To estimate size and shape of pelvis
  • To obtain vaginal secretions to detect infection or cervical cancer (Pap smear)

Late pregnancy:

  • To assess condition of cervix and station of baby
  • To obtain vaginal secretions to detect infection, if indicated
 

 

  • Exam may cause dark brown or reddish vaginal discharge.
  • Exam may increase risk of infection or premature rupture of membranes
Urine tests First prenatal visit:

  • To confirm pregnancy

Each prenatal visit:

  • To detect infection
  • To check for sugar and acetone, which might indicate diabetes
  • To check for protein, which might indicate preeclampsia or infection
 

 

  • Urine test may be less accurate than blood tests to confirm pregnancy.
  • Urine tests are less accurate than blood tests to confirm diabetes.
Blood tests First or second prenatal visit:

  • To confirm pregnancy
  • To determine blood type, Rh type
  • To test for anemia (hematocrit and hemoglobin)
  • To test for German measles immunity
  • To test for syphilis
  • To test for antibodies to human immunodeficiency virus (HIV)
  • To test for antibodies to hepatitis B virus
 

 

 

 

  • Some tests will be repeated.
  • Some caregivers do not perform all these tests.
  • Anemia may be treated with iron supplements or diet changes.
Blood pressure test Each prenatal visit:

  • To detect pregnancy-induced hypertension (PIH) or preeclampsia
Maternal weight check Each prenatal visit:

  • To detect sudden weight gain that could be due to preeclampsia
  • To help monitor mother’s nutritional status
Abdominal examination Each prenatal visit:

  • To measure the growth of the uterus (fundal height) which indicates fetal growth and gestational age

Last weeks of pregnancy:

  • To estimate size and position of the fetus (Leopold’s maneuvers)
  • To estimate amniotic fluid volume
  • To detect breech presentation
 

 

 

 

  • If a problem is suspected, ultrasound visualization is usually recommended.

 

 

 

 

 

  • If breech, mother may use self-help measures to turn fetus; medical professional may perform external version.
Listening to fetal heart rate (FHR)The FHR is heard through the mother’s abdomen with a fetal stethoscope or a Doppler, which uses ultrasound. Each prenatal visit after the FHR can be heard (about 12 weeks):

  • To assess the well-being of the fetus
 

 

 

 

 

  • Hearing the FHR increases the expectant parent’s feelings of attachment for their baby and makes the baby seem more real.
Breast exam Once or more during pregnancy:

  • To check for flat or inverted nipples
  • To assess condition of breasts for ability to breastfeed
  • To detect any breast abnormalities including screening for breast cancer
 

 

 

  • If her nipples are flat or inverted, the mother can use methods to draw them out.
  • Breast self-exams should be performed regularly throughout pregnancy.
Alpha-Fetoprotein (AFP)A blood test that measures the level of alpha-fetoprotein, a substance produced by the fetal liver that crosses to the maternal blood-stream in predictable amounts. Test results are usually available in one week. 16 to 18 weeks gestation:

  • To screen for a baby with a neural tube defect (spina bifida, anencephaly), the presence of twins, or fetal death (high level of AFP)
  • To screen for Down’s syndrome (low level of AFP)
 

 

 

 

  • If AFP test results are outside the normal range, then further testing includes a repeat blood test to confirm findings, ultrasound, genetic counseling, and possible amniocentesis.
  • The test will not detect all cases of neural tube defects or Down’s syndrome.
  • There is a high rate of false positives (the test indicated a problem when there is none).
  • The test’s accuracy is questionable if the due date is unclear.
  • The risk of neural tube defects is about 1 to 2 per 1,000 births.
  • Insulin-dependent diabetics usually show an AFP level lower than others.
  • The test helps parents plan management of pregnancy or birth (they could terminate the pregnancy, plan a cesarean if spina bifida is detected, or prepare of a child with a disability).
Prenatal risk profile (Triple Screen)A blood test that measures levels of three substances: human chorionic gonadotrophin (hCG), a hormone produced by the chorionic villi; estriol, a by-product of estrogen metabolism; and maternal serum alpha-fetoprotein (AFP 15 to 18 weeks gestation:

  • To screen for Down’s syndrome (low levels of estriol and AFP combined with high levels of hCG)
 

 

 

 

  • Initial studies indicate that the Triple Screen is more accurate than AFP screening alone in detecting Down’s syndrome (2 to 3 times more accurate in women under 35; 50 percent more accurate in women over 35).
  • It is useful those who do not have amniocentesis, although it does not detect the hundreds of other possible inherited disorders that can be detected by amniocentesis or chorionic villus sampling.
  • It is a screening procedure only; this test may miss 20 to 30 percent of Down’s syndrome pregnancies in women over 35, and 40 percent in women under 35.
Glucose screeningA blood sample is taken from the mother one hour after she drinks a sugary (glucose) drink or eats a special carbohydrate meal. 24 or 30 weeks gestation (commonly 28 weeks):

  • To screen for gestational diabetes, which, if untreated, may cause problems for mother and baby
 

 

 

 

  • If the mother’s blood sugar is elevated, a longer and more sensitive glucose tolerance test (GTT) is planned.
  • Approximately 85 percent of those with an elevated blood sugar in the screening test will be found to have normal blood sugar levels in the GTT.
  • Detection of diabetes enables treatment to avoid problems for the mother of baby.

 

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